MyBioSource.com's Anti-alpha-Adaptin antibody (monoclonal) is a Mouse monoclonal antibody. The Anti-alpha-Adaptin antibody (monoclonal) was generated using ADTAA, and AP2A1 as the antigen. It reacts with Human, and Rat. This antibody has been shown to work in applications such as: Western Blot.
Description
Description: Mouse IgG monoclonal antibody for alpha-Adaptin, adaptor-related protein complex 2, alpha 1 subunit (AP2A1) detection. Tested with WB in Human, rat. No cross reactivity with other proteins. Uniprot ID: O95782
Background: Alpha Adaptin, also known as adaptor related protein complex, alpha 1 subunit. The alpha adaptins are exclusively found in the endocytic coated vesicles. Huntingtin-interacting protein 1(HIP1) is enriched in membrane-containing cell fractions and has been implicated in vesicle trafficking. Waelter et al.(2001) identified 3 HIP1-associated proteins, clathrin heavy chain(CLTC)and alpha-adaptin A and C. Coat proteins of approximately 100-kD(adaptins) are components of the adaptor complexes which link clathrin to receptors in coated vesicles. The alpha-adaptins separate into two bands on SDS gels